Persistent hiccups can be more than a simple and short-lived nuisance and therefore sometimes call for serious consideration. It is usually associated with a bad prognosis Conclusions: Persistent hiccup is often associated with organic conditions, specially advanced tumors of the digestive tract. Death occurred during the first three months of follow up in 61%. Average hospital stay was 13 days (range 3-90 days). Chlorpromazine was the first choice treatment in 23 patients, but seven required a second line drug. Twelve patients had a history of exposure to drugs that potentially could cause hiccups, mainly corticosteroids and benzodiazepines. The most common possible causes were digestive tract disorders, followed by central nervous system diseases. In twenty one patients, at ¡east one organic etiology was identified, and thirteen patients presented two or more possible associated conditions. Nineteen (79%) were admitted because of persistent hiccups. Results: Twenty four patients (age 47 to 91 years, 23 males) were studied. Patients and Methods: A retrospective study and prospective follow up of patients admitted for hiccup in Hospital Clínico de Santiago de Compostela between January 1998 and May 2005. Aim: To report clinical features of patients admitted in a hospital due to hiccup. There is not much information about persistent and refractory hiccups. Se pone tratamiento basado en medidas populares, y medicamentos del síntoma fundamental con cloropromacina (tabletas de 25mg): 1 tableta cada 8 horas, obteniendo mejoría ostensible del mismo, hasta el momento en que se diagnóstica la causa etiológica, donde se pone tratamiento específico de la enfermedad de reflujo gastroesofágico con omeprazol (20mg): 1 Cápsula cada 12 horas y domperidona, obteniendo la desaparición del síntoma que causó la consulta inicial del paciente.īackground: Although common and usually benign, hiccups can be an extremely uncomfortable disease. Se le realiza interrogatorio y examen físico minucioso, electrocardiograma, rayos X de tórax y abdomen, analítica sanguínea, ultrasonido abdominal, Endoscopia superior, tomografía de tórax y abdomen, además de Manometría esofágica y la prueba terapéutica con omeprazol, diagnosticándose una enfermedad de reflujo gastroesofágico. Las causas del singultus pueden ser gastrointestinales (reflujo gastroesofágico, hernia del hiato, esofagitis, úlcera gástrica, pancreatitis, carcinoma esofágico, masas hepáticas, ascitis, cirugía abdominal), neurológicas, vasculares, torácicas, metabólicas, tóxicas, fármacos y otras. Esta entidad infrecuente se presenta en un hombre de 63 años, con historia de singultus desde hace tres años, que aparece fundamentalmente posterior a la ingestión de alimentos y persiste durante varios minutos u horas, todos los días. ↵National Institute for Health and Care Excellence.El hipo persistente (singultus) es aquel que se presenta en forma de un ataque prolongado o ataques recurrentes durante un tiempo determinado, generalmente más de 48 horas, suele resolverse sin tratamiento farmacológico, pero puede ser necesario administrarlo y plantear su estudio etiológico.Inouye SK, Westendorp RG, Saczynski JS.Occurrence and outcome of delirium in medical in-patients: a systematic literature review. Recent insights on prevalence and correlations of hypoactive delirium.
↵Peritogiannis V, Bolosi M, Lixouriotis C, Rizos DV.The delirium subtypes: a review of prevalence, phenomenology, pathophysiology, and treatment response. Impact of delirium and recall on the level of distress in patients with advanced cancer and their family caregivers. The delirium experience: delirium recall and delirium-related distress in hospitalized patients with cancer, their spouses/caregivers, and their nurses.
“I can remember sort of vivid people…but to me they were plasticine.” Delusions on the intensive care unit: what do patients think is going on?PLoS One2016 11:e0153775. ↵Darbyshire JL, Greig PR, Vollam S, Young JD, Hinton L.Validation of the 4AT, a new instrument for rapid delirium screening: a study in 234 hospitalised older people. ↵Bellelli G, Morandi A, Davis DH, et al.
Diagnostic and statistical manual of mental disorders. Motor subtypes of delirium: past, present and future.